Vision Loss from Ozempic, Wegovy, or Mounjaro?

Another serious eye condition being linked to Ozempic, Wegovy, and other GLP-1 drugs is neovascular age-related macular degeneration (nAMD). This progressive disease can lead to permanent central vision loss. 

nAMD is the more aggressive (wet) form of age-related macular degeneration. It occurs when abnormal blood vessels grow beneath the retina and leak fluid or blood, damaging the central part of the retina responsible for sharp, detailed vision.  

Ozempic and the Risk of nAMD 

A recent article in JAMA Ophthamology (June 2025) suggests that vascular changes triggered by GLP-1 activity may trigger or worsen nAMD in some patients, especially those who are older, diabetic, or already at risk for macular degeneration. In patients using Ozempic, symptoms of nAMD were rapid-onset, occurring after the start of treatment, and were sometimes misdiagnosed as typical diabetic vision changes.  

nAMD Symptoms May Include: 

• Distortion of straight lines (metamorphopsia)
• Blurred or fuzzy central vision 
• Dark or empty areas in the center of vision
• Difficulty seeing fine detail, even with glasses
• Sudden worsening of visual acuity 

The aggressive nature of nAMD means early detection plays a key role in preventing permanent vision loss. Drug manufacturers have a responsibility to warn about serious side effects, including those that are newly emerging in post-market surveillance. Our attorneys are investigating claims where patients were not adequately warned about the risk of nAMD and suffered serious, irreversible vision damage as a result.  If you have suffered serious eye problems after using a GLP-1 drug, Schlesinger Law Offices may be able to help. Our attorneys are actively reviewing and retaining new cases nationwide. 

Blurry Vision and Eye Pain: A Warning Sign Worth Noticing 

Some people experience blurry vision or eye pain shortly after starting GLP-1 medications like Ozempic, Wegovy, or Mounjaro. While these symptoms are sometimes temporary and related to fluid shifts in the eye from rapid blood sugar changes, they should never be ignored. In many cases, these early symptoms may signal the onset of more serious conditions that can lead to permanent vision loss if left undiagnosed. 

Rapid drops in blood glucose, a known effect of GLP-1 drugs, can change the shape of the eye’s lens, distorting focus and causing blurry or cloudy vision. This effect may resolve on its own, but the sudden onset of visual symptoms should always be evaluated, especially in patients with diabetes or a history of eye disease. 

Blurry vision or eye discomfort may also be early warning signs of: 

• Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) – a sudden loss of blood flow to the optic nerve that can cause irreversible vision loss
• Diabetic Retinopathy – a progressive condition involving damage to blood vessels in the retina, which may worsen during rapid improvements in blood sugar
• Other retinal or optic nerve disorders, including neovascular macular degeneration (nAMD) or optic neuropathy 

The FDA Adverse Event Reporting System (FAERS) has logged hundreds of reports of blurry vision associated with Ozempic use alone. Clinical trials also list visual disturbances like floaters and blurred vision as less common but documented side effects. 

If you experience any vision changes while using a GLP-1 drug, it’s important to speak with your doctor immediately. What seems minor at first could be a warning sign of something more serious.